| 1 | Josef Martínez
Atlanta United FC | Atlanta United FC | 39 | 35 |
| 2 | Zlatan Ibrahimovic
LA Galaxy | LA Galaxy | 27 | 22 |
| 3 | Bradley Wright-Phillips
New York Red Bulls | New York Red Bulls | 36 | 20 |
| - | Gyasi Zardes
Columbus Crew SC | Columbus Crew SC | 36 | 20 |
| 5 | Mauro Manotas
Houston Dynamo FC | Houston Dynamo FC | 33 | 19 |
| 6 | Ignacio Piatti
CF Montréal | CF Montréal | 32 | 16 |
| 7 | David Villa
New York City FC | New York City FC | 26 | 15 |
| - | Nemanja Nikolic
Chicago Fire FC | Chicago Fire FC | 31 | 15 |
| - | Damir Kreilach
Real Salt Lake | Real Salt Lake | 36 | 15 |
| 10 | Kei Kamara
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 28 | 14 |
| - | Carlos Vela
Los Angeles FC | Los Angeles FC | 29 | 14 |
| - | Dániel Sallói
Sporting Kansas City | Sporting Kansas City | 33 | 14 |
| - | Ola Kamara
LA Galaxy | LA Galaxy | 31 | 14 |
| - | Diego Valeri
Portland Timbers | Portland Timbers | 38 | 14 |
| 15 | Raúl Ruidíaz
Seattle Sounders FC | Seattle Sounders FC | 16 | 13 |
| - | Dom Dwyer
Orlando City SC | Orlando City SC | 26 | 13 |
| - | Daniel Royer
New York Red Bulls | New York Red Bulls | 33 | 13 |
| - | Sebastian Giovinco
Toronto FC | Toronto FC | 28 | 13 |
| - | Sebastián Blanco
Portland Timbers | Portland Timbers | 37 | 13 |
| - | Miguel Almirón
Atlanta United FC | Atlanta United FC | 37 | 13 |
| 21 | Adama Diomande
Los Angeles FC | Los Angeles FC | 19 | 12 |
| - | Wayne Rooney
D.C. United | D.C. United | 21 | 12 |
| - | Ismael Tajouri
New York City FC | New York City FC | 30 | 12 |
| - | Aleksandar Katai
Chicago Fire FC | Chicago Fire FC | 33 | 12 |
| - | Danny Hoesen
San Jose Earthquakes | San Jose Earthquakes | 34 | 12 |
| - | Diego Rossi
Los Angeles FC | Los Angeles FC | 33 | 12 |
| - | Cristian Penilla
New England Revolution | New England Revolution | 33 | 12 |
| 28 | Cory Burke
Philadelphia Union | Philadelphia Union | 30 | 11 |
| - | Romain Alessandrini
LA Galaxy | LA Galaxy | 26 | 11 |
| - | Darwin Quintero
Minnesota United FC | Minnesota United FC | 27 | 11 |
| - | Alberth Elis
Houston Dynamo FC | Houston Dynamo FC | 30 | 11 |
| - | Teal Bunbury
New England Revolution | New England Revolution | 32 | 11 |
| - | Albert Rusnák
Real Salt Lake | Real Salt Lake | 33 | 11 |
| 34 | Diego Rubio
Sporting Kansas City | Sporting Kansas City | 23 | 10 |
| - | Darren Mattocks
D.C. United | D.C. United | 26 | 10 |
| - | Christian Ramirez
Los Angeles FC | Los Angeles FC | 8 | 10 |
| - | Fafà Picault
Philadelphia Union | Philadelphia Union | 30 | 10 |
| - | Chris Wondolowski
San Jose Earthquakes | San Jose Earthquakes | 34 | 10 |
| - | Johnny Russell
Sporting Kansas City | Sporting Kansas City | 34 | 10 |
| - | Jonathan Osorio
Toronto FC | Toronto FC | 30 | 10 |
| - | Valeri Qazaishvili
San Jose Earthquakes | San Jose Earthquakes | 33 | 10 |
| - | Luciano Acosta
D.C. United | D.C. United | 34 | 10 |
| 43 | Dominique Badji
FC Dallas | FC Dallas | 11 | 9 |
| - | Yamil Asad
D.C. United | D.C. United | 31 | 9 |
| - | Nicolás Lodeiro
Seattle Sounders FC | Seattle Sounders FC | 29 | 9 |
| - | Diego Fagundez
New England Revolution | New England Revolution | 33 | 9 |
| - | Maximiliano Moralez
New York City FC | New York City FC | 35 | 9 |
| 48 | Cristian Techera
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 21 | 8 |
| - | Víctor Vázquez
Toronto FC | Toronto FC | 21 | 8 |
| - | Samuel Armenteros
Portland Timbers | Portland Timbers | 28 | 8 |